Tuesday, November 13, 2012

Further IVF Improvements: Single Embryo Transfer


IVF has dramatically improved in many ways.  Pharmaceutical agents are more pure and numerous.  Our understanding of how to improve the number and quality of oocytes has been revolutionized.  Laboratory protocols have also advanced, as well as ultrasound technology. Single Embryo Transfer (SET) is another new protocol, used to reduce the likelihood of twins or triplets. Although most parents are happy to be pregnant with multiples, medically speaking, a single baby is associated with much fewer complications: in utero, during birth, and developmentally as an infant.

The last decade has been focused on reduction of high order multiple pregnancies such as triplets.  This decade we are focusing on reduction of twins.  It is well established that the best obstetrical outcome is with a singleton pregnancy.  We are now able to offer some patients single embryo blastocyst transfer.  Typically this will be an individual who is less than 35 years of age with high quality blastocysts who will have  additional embryos to freeze in case pregnancy does not occur immediately.  Those patients are expected to have a clinical pregnancy rate per embryo transfer of at least 50%.  Many of these patients are enrolled in our money back IVF guarantee program which lets them continue treatment without financial risk till live birth.  These program participants can do up to 3 fresh and 3 frozen cycles at no extra program cost.  The end point of this program is live birth or a 70% refund of all fees.   Twin rates with single embryo transfer are less than 1% vs. 25% with a 2 embryo transfer.


We are delighted that single embryo transfer is a reality!  It has taken decades of our work and your patience.  We expect this effort will continue for another decade as technology continues to evolve.